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Maintaining a balanced diet rich in fruits, vegetables, and whole grains provides the body with essential nutrients for testosterone production. Regular exercise, particularly strength training, can also help stimulate testosterone production and improve overall health. Improved insulin sensitivity may occur in patients treated with androgens who achieve normal testosterone plasma concentrations following replacement therapy. Therefore, the dosage of hypoglycaemic agents may need to be lowered. In patients suffering from severe cardiac, hepatic or renal insufficiency or ischaemic heart disease, treatment with testosterone may cause severe complications characterised by oedema with or without congestive cardiac failure. Nebido should be used only if hypogonadism (hyper- and hypogonadotrophic) has been demonstrated and if other aetiology, responsible for the symptoms, has been excluded before treatment is started.
Treatment with high doses of testosterone preparations commonly may reversibly stop or reduce sperm production (see also under “Possible side effects”). Following the use of hormonal substances such as androgen compounds, cases of benign (non-cancerous) and malignant (cancerous) liver tumours have been observed to occur. Abuse of testosterone, especially if you take too much of this medicine alone or with other anabolic androgenic steroids, can cause serious health problems to your heart and blood vessels (that can lead to death), mental health and/or the liver. Each vial with 4 ml solution for injection contains 1000 mg testosterone undecanoate. Treatment with high doses of testosterone preparations commonly may reversibly stop or reduce sperm production (see also under “Possible side effects”). It may be necessary to adjust the dose of your blood sugar reducing medicine.
It also performs functions, e.g. in the skin, muscles, skeleton, kidney, liver, bone marrow, and CNS. The active form, testosterone, is formed by cleavage of the side chain. The most frequently reported undesirable effects during treatment with Nebido are acne and injection site pain. Nebido should be permanently withdrawn if symptoms of excessive androgen exposure persist or reappear during treatment with the recommended dosage regimen. Androgens may accelerate the progression of sub-clinical prostatic cancer and benign prostatic hyperplasia.
Like other androgens, testosterone may increase the effect of insulin. Following the use of hormonal substances such as androgen compounds, cases of benign (non-cancerous) and malignant (cancerous) liver tumours have been observed to occur. If you https://shop.grubin.rs/norditropin-flexpro-15-iu-novo-nordisk-a/ are suffering from severe heart, liver or kidney disease, treatment with Nebido may cause severe complications in the form of water retention in your body sometimes accompanied by (congestive) heart failure. NEBIDO uses a slow-release mechanism, so it can take longer to experience the full effects compared to other testosterone formulations.
In children, exposure to testosterone can cause premature puberty and developmental abnormalities. Testosterone production naturally declines with age in most men, beginning around the late 30s or early 40s. This gradual decrease can lead to a constellation of symptoms known as age-related hypogonadism. After removal of the plastic cap (A) do not remove the metal ring (B) or the crimp cap ©. The contents of a vial are to be injected intramuscularly immediately after opening the vial. At cold storage temperatures the properties of this oil-based solution might temporarily change (e.g. higher viscosity, cloudiness).
Serum levels below normal range would indicate the need for a shorter injection interval. In case of high serum levels an extension of the injection interval may be considered. Local guidelines for safety monitoring under testosterone replacement therapy should be taken into consideration. Measurements should be performed at the end of an injection interval and clinical symptoms considered. These serum levels should be within the lower third of the normal range. Serum levels below normal range would indicate the need for a shorter injection interval.
Before your doctor injects Nebido, he/she will examine you to check that you do not have prostate cancer. Your doctor will regularly examine your prostate and breast, especially if you are elderly. In 2013, a study aimed to evaluate the efficacy of testosterone undecanoate therapy on bone mineral density (BMD) and biochemical markers of bone turnover in elderly males with osteoporosis and low serum testosterone levels.
Your doctor will inject Nebido (1 ampoule / vial) very slowly into a muscle. This is enough to maintain sufficient testosterone levels without leading to a build-up of testosterone in the blood. Medical examination/Follow-up Male hormones may increase the growth of prostate cancer and enlarged prostate glands (benign prostatic hypertrophy).
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